Arsenal have won both of their opening two Premier League matches for the fourth time in the past five seasons and are aiming to make it three on the bounce against Fulham this afternoon at the Emirates.
Arsenal forward Gabriel Jesus could make his first appearance appearance of the season after recovering from a knee injury.
Takehiro Tomiyasu is banned after his controversial sending-off last weekend.
Former Arsenal attacker Willian is a doubt to face his former club with an Achilles problem, but Joao Palhinha could start after his comeback from injury as a substitute last week
Fulham captain Tim Ream is also suspended after his dismissal in the defeat by Brentford.
Eddie Nketiah has scored 14 goals in his last 16 starts at Emirates Stadium in all competitions.
Leandro Trossard has registered 10 assists since his Arsenal debut in January, more than any other Premier League player in that time. Three of those came against Fulham in March.
Brazilian defender Gabriel has scored in three of his four Premier League appearances against Fulham, including a late winner in this fixture last season.
Arsenal are unbeaten in each of their last 13 Premier League London derbies (W11, D2).
Fulham have never won an away match against Arsenal in any competition (D6, L25), including all 30 league fixtures - the most one team has faced another away from home without winning in English league history.
The Cottagers are winless in their last 10 Premier League games against Arsenal (D2, L8) and have failed to keep a clean sheet in any of their past 16 games against the Gunners.
The Emirates Stadium has seen 81 Premier League goals at an average of 4.05 per game since the start of last season, more than at any other venue.
Bukayo Saka could set a new club record by playing in his 83rd consecutive Premier League match.
Fulham could win their opening two top-flight away games for the first time in what is their 29th season in the top tier.The Cottagers have won just once in their past 19 top-flight London derbies (D4, L14).
Marco Silva's side took one point from a possible 30 in their 10 games against sides that finished in the top five last season, losing all five away matches by a single-goal margin.
Raul Jimenez has not scored in any of his last 25 Premier League games.